Table 1 Comparison of clinicopathologic characteristics according to the Gli1 expression in GA
From: Gli1 regulates stemness characteristics in gastric adenocarcinoma
| Variable | N | Gli1(−)n (%) | Gli1(+)n (%) | χ2 | R | P |
|---|---|---|---|---|---|---|
| Age (years) | 1.448 | 0.093 | 0.229 | |||
| < 65 | 109 | 32(29.4) | 77(70.6) | |||
| ≥ 65 | 60 | 13(21.7) | 47(78.3) | |||
| Sex | 1.347 | 0.089 | 0.246 | |||
| Male | 106 | 25(23.6) | 81(76.4) | |||
| Female | 63 | 20(31.7) | 43(68.3) | |||
| Tumor size (cm) | 0.759 | 0.065 | 0.384 | |||
| < 4.5 | 63 | 19(30.2) | 44(69.8) | |||
| ≥ 4.5 | 106 | 26(24.5) | 80(75.5) | |||
| Tumor grade | 15.771 | 0.049 | 0.001* | |||
| Well | 31 | 14(45.2) | 17(54.8) | |||
| Moderate | 66 | 11(16.7) | 55(83.3) | |||
| Poor | 72 | 20(27.8) | 52(72.2) | |||
| Tumor location | 1.943 | 0.024 | 0.584 | |||
| Antrum | 93 | 23(24.7) | 70(75.2) | |||
| Cardia | 3 | 0(0) | 3(100.0) | |||
| Body | 63 | 20(31.7) | 43(68.3) | |||
| Mix | 10 | 2(20.0) | 8(80.0) | |||
| pT stage | 9.034 | 0.218 | 0.029* | |||
| 1 | 35 | 16(45.7) | 19(54.3) | |||
| 2 | 38 | 11(28.9) | 27(71.1) | |||
| 3 | 92 | 17(18.5) | 75(81.5) | |||
| 4 | 4 | 1(25.0) | 3(75.0) | |||
| Lymph node metastasis | 1.949 | 0.105 | 0.163 | |||
| Negative | 144 | 41(28.5) | 103(71.5) | |||
| Positive | 25 | 4(16.0) | 21(84.0) | |||
| Distant metastasis | 7.403 | 0.208 | 0.007* | |||
| Negative | 151 | 45(29.8) | 106(70.2) | |||
| Positive | 18 | 0(0) | 18(100.0) | |||
| Clinical stage | 12.799 | 0.262 | 0.005* | |||
| 1 | 44 | 18(40.9) | 26(59.1) | |||
| 2 | 34 | 11(32.4) | 23(67.6) | |||
| 3 | 73 | 16(21.9) | 57(78.1) | |||
| 4 | 18 | 0(0) | 18(100.0) | |||
| Gross type | 5.365 | 0.177 | 0.021* | |||
| Early gastric cancer | 37 | 16(43.2) | 21(56.8) | |||
| Advanced gastric cancer | 132 | 29(22.0) | 103(78.0) | |||
| Histological type | 0.389 | 0.032 | 0.823 | |||
| Intestinal | 91 | 26(28.6) | 65(71.4) | |||
| Diffuse | 70 | 17(24.3) | 53(75.7) | |||
| Mix | 8 | 2(25.0) | 6(75.0) | |||
| Survival | 23.883 | 0.375 | < 0.001* | |||
| Die | 78 | 7(9.0) | 71(91.0) | |||
| Alive | 91 | 38(41.8) | 53(58.2) |