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|
Osteosarcoma subtype
|
Positives Casesb (%)
|
Extent of staininga
|
Strong-intensity staining (%)
|
|---|
|
0
|
1+
|
2+
|
3+
|
4+
|
5+
|
|---|
|
Osteoblastic (n = 55)
|
50 (90.9)
|
3
|
2
|
13
|
18
|
15
|
4
|
39 (70.9)
|
|
Chondroblastic (n = 13)
|
10 (76.9)
|
2
|
1
|
3
|
4
|
2
|
1
|
7 (53.8)
|
|
Fibroblastic (n = 6)
|
2 (33.3)
|
3
|
1
|
0
|
2
|
0
|
0
|
2 (33.3)
|
|
Telangiectatic (n = 4)
|
3 (75)
|
1
|
0
|
1
|
2
|
0
|
0
|
2 (50)
|
|
giant cell-rich (n = 3)
|
2 (66.7)
|
1
|
0
|
1
|
1
|
0
|
0
|
1 (33.3)
|
|
Total (n = 81)
|
67 (82.7)
|
10
|
4
|
18
|
27
|
17
|
5
|
51 (63.0)
|
- a0, no staining; 1+, < 5%; 2+, 5–25%; 3+, 26–50%; 4+, 51–75%;5+, 76–100%
- bThe positive KPNA2 staining was defined as nucleus staining in at least 5% cells