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Table 3 Expression and extent of KPNA2 Immunohistochemical staining in osteosarcoma subtypes

From: KPNA2 expression is a potential marker for differential diagnosis between osteosarcomas and other malignant bone tumor mimics

Osteosarcoma subtype Positives Casesb (%) Extent of staininga Strong-intensity staining (%)
0 1+ 2+ 3+ 4+ 5+
Osteoblastic (n = 55) 50 (90.9) 3 2 13 18 15 4 39 (70.9)
Chondroblastic (n = 13) 10 (76.9) 2 1 3 4 2 1 7 (53.8)
Fibroblastic (n = 6) 2 (33.3) 3 1 0 2 0 0 2 (33.3)
Telangiectatic (n = 4) 3 (75) 1 0 1 2 0 0 2 (50)
giant cell-rich (n = 3) 2 (66.7) 1 0 1 1 0 0 1 (33.3)
Total (n = 81) 67 (82.7) 10 4 18 27 17 5 51 (63.0)
  1. a0, no staining; 1+, < 5%; 2+, 5–25%; 3+, 26–50%; 4+, 51–75%;5+, 76–100%
  2. bThe positive KPNA2 staining was defined as nucleus staining in at least 5% cells
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