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Scoring system
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Cytoplasmic TWIST1 N (%)
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Nuclear TWIST1 N (%)
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Cytoplasmic CD105 N (%)
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Endothelial CD105 N (%)
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|---|
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Intensity of staining
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No staining (0)
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0 (0.0)
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0 (0.0)
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44 (21.2)
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0 (0.0)
|
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Weak (+ 1)
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111 (49.8)
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69 (30.9)
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161 (77.4)
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0 (0.0)
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Moderate (+ 2)
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106 (47.5)
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123 (55.2)
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3 (1.4)
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25 (12.0)
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Strong (+ 3)
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6 (2.7)
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31 (13.9)
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0 (0.0)
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183 (88.0)
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Percentage of positive tumor cells
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< 25%
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0 (0.0)
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0 (0.0)
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121 (58.2)
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0 (0.0)
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25–50%
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0 (0.0)
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1 (0.4)
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60 (28.8)
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0 (0.0)
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51–75%
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3 (1.3)
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20 (9.0)
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13 (6.3)
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6 (2.9)
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> 75%
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220 (98.7)
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202 (90.6)
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14 (6.7)
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202 (97.1)
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H-score cut off
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149
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172
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26
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284
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Low
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113 (50.7)
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87 (39.0)
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121 (58.2)
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34 (16.3)
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High
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110 (49.3)
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136 (61.0)
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87 (41.8)
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174 (83.7)
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Total
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223
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223
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208
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208
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- H-score indicates histological score