Fig. 7

Comparison of immunoexpression of the key proteins of the invadopodia in the different histological grades. Tks5 did not present statistical difference in the different groups (a). Cortactin was more expressed in degree I of differentiation in relation to grade II and III (b). Immunostaining values for TKs4 did not present statistical differences in the different groups (c). MT1-MMP was more expressed in cases of lower cell differentiation (d). * p < 0.05, ** p = 0.001, *** p = 0.0001