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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  2. The feasibility of evaluating an objective grading of cervical intraneoplasia lesions (CIN) is attempted using an automatic computerized system able to measure several valuable parameters with special referenc...

    Authors: Michel Jondet, Régis Agoli-Agbo and Louis Dehennin

    Citation: Diagnostic Pathology 2010 5:7

    Content type: Research

    Published on:

  3. The presence of crystalline inclusions in plasma cell myeloma is a rare phenomenon and cases have been reported with rod, needle, and rectangular shaped crystals. Here, we present a case of IgG lambda restrict...

    Authors: Andres Matoso, Tina Rizack and Diana O Treaba

    Citation: Diagnostic Pathology 2010 5:6

    Content type: Case Report

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  5. A 60-year-old Caucasian male underwent a total pancreatectomy for a mixed type pancreatic intraductal papillary mucinous neoplasm (IPMN) arising in the main and secondary pancreatic ducts. During surgery, a su...

    Authors: Dimitrios Tsapralis, Alexandros Charalabopoulos, Eva Karamitopoulou, Dimitrios Schizas, Konstantinos Charalabopoulos, Theodoros Liakakos and Anastasios Macheras

    Citation: Diagnostic Pathology 2010 5:4

    Content type: Case Report

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  6. Carcinomas of unknown primary (CUP) represent approximately 3%-5% of malignant neoplasms. Identifying the tissue of origin (TOO) in these tumors allows for more specific treatment and improves outcomes. Howeve...

    Authors: Federico A Monzon, Fabiola Medeiros, Maureen Lyons-Weiler and W David Henner

    Citation: Diagnostic Pathology 2010 5:3

    Content type: Research

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  7. A rare case is presented of a 61-year-old man with a malignant peripheral nerve sheath tumor associated with neurofibromatosis type 1, with metastasis to the heart. The primary tumor originated in the right th...

    Authors: Masanori Kitamura, Naoki Wada, Shigenori Nagata, Norishige Iizuka, Yu-Fen Jin, Miki Tomoeda, Michiko Yuki, Norifumi Naka, Nobuhito Araki, Chikao Yutani and Yasuhiko Tomita

    Citation: Diagnostic Pathology 2010 5:2

    Content type: Case Report

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  8. Immunocompromised patients who develop invasive filamentous mycotic infections can be efficiently treated if rapid identification of the causative fungus is obtained. We report a case of fatal necrotic pneumon...

    Authors: Véronique Hofman, Abdelmajid Dhouibi, Catherine Butori, Bernard Padovani, Martine Gari-Toussaint, Dea Garcia-Hermoso, Michèle Baumann, Nicolas Vénissac, Gieri Cathomas and Paul Hofman

    Citation: Diagnostic Pathology 2010 5:1

    Content type: Case Report

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  9. Giant cell tumor, excluding its prototype in bone, is usually a benign but local aggressive neoplasm originating from tendon sheath or soft tissue. Malignant behavior is uncommon. Visceral organ involvement in...

    Authors: Kemal Behzatoğlu, Haydar Durak, Şule Canberk, Övgü Aydın, Gülben Erdem Huq, Meltem Oznur, Gülzade Özyalvaçlı and Pelin Yıldız

    Citation: Diagnostic Pathology 2009 4:48

    Content type: Case Report

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  12. We report a case of embolism of the sclerosant dye with subsequent formation of foreign-body giant cell reaction within the veins of pulmonary and portal circulation in an autopsy case of hepatocellular carcin...

    Authors: Kirti Gupta, Rakesh K Vasishta, Usha Dutta, Rakesh K Kochhar and Kartar Singh

    Citation: Diagnostic Pathology 2009 4:45

    Content type: Case Report

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  14. Recently, fimbriae have been identified as a possible arising site for the pelvic serous carcinoma (PSC) both in BRCA-positive and BRCA-negative women. Although non-invasive (intraepithelial) serous adenocarci...

    Authors: Yuki Fukumura, Akiko Masaoka, Toshio Naito, Miki Kimura and Takashi Yao

    Citation: Diagnostic Pathology 2009 4:43

    Content type: Case Report

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  15. Primary neoplasms of the mesentery are very rare. They are usually of mesenchymal origin and include desmoid tumor, lipoma, liposarcoma, and fibrosarcoma. Metastatic carcinomas and lymphoma are more common. We...

    Authors: Dina El Demellawy, Chaturika Herath, Francoise Truong, Ahmed Nasr and Salem Alowami

    Citation: Diagnostic Pathology 2009 4:42

    Content type: Case Report

    Published on:

  16. Different molecular alterations have been described in endometrioid endometrial carcinoma (EECA). Among them the most frequently altered is loss of the PTEN protein, a tumor suppressor gene. The purpose of thi...

    Authors: Soheila Sarmadi, Narges Izadi-Mood, Kambiz Sotoudeh and Seyed Mohammad Tavangar

    Citation: Diagnostic Pathology 2009 4:41

    Content type: Research

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  17. Worldwide, over one million people commit suicide every year. In the United States, the majority of these cases consist of gunshot wounds, hangings, and drug overdoses. Nevertheless, on rare occasions will ind...

    Authors: Daniel C Lingamfelter, Erin Duddlesten and Reade A Quinton

    Citation: Diagnostic Pathology 2009 4:40

    Content type: Case Report

    Published on:

  18. Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the metabolism of folate. The non-synonymous single nucleotide polymorphism (nsSNP), C677T (Ala>Val, rs1801133), has been verified to impair enzym...

    Authors: Fei Jin, Li-Shuai Qu and Xi-Zhong Shen

    Citation: Diagnostic Pathology 2009 4:39

    Content type: Research

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  19. CD10 antigen is a 100-kDa-cell surface zinc metalloendopeptidase and it is expressed in a variety of normal and neoplastic lymphoid and nonlymphoid tissues. The aim of this study was to evaluate CD10 expressio...

    Authors: Burak Bahadir, Kemal Behzatoglu, Sibel Bektas, Erol R Bozkurt and Sukru O Ozdamar

    Citation: Diagnostic Pathology 2009 4:38

    Content type: Research

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  20. Primary liver tumors in children are rare with malignant hepatoblastoma being the most common neoplasm. In this report, we describe the diagnosis and clinical management of a large liver tumor in a 3-year-old ...

    Authors: Alexander Moll, Alexander Krenauer, Uta Bierbach, Holger Till, Wolfgang Hirsch, Ivo Leuschner, Nicole Schmitz, Christian Wittekind and Thomas Aigner

    Citation: Diagnostic Pathology 2009 4:37

    Content type: Database

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  21. Increase of EGFR gene copy number consequent to gene amplification and/or polysomy of chromosome 7 has been significantly associated with better clinical outcome in Non Small Cell Lung Cancer (NSCLC) patients tre...

    Authors: Laura Casorzo, Mara Corigliano, Paolo Ferrero, Tiziana Venesio and Mauro Risio

    Citation: Diagnostic Pathology 2009 4:36

    Content type: Methodology

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  22. Distinction between non-neoplastic and neoplastic bladder lesions is therapeutically and prognostically important. Our objective is to describe the use of double immunohistochemistry (DIHC) for p53+CK20 as a t...

    Authors: Isil Z Yildiz, Rosemary Recavarren, Henry B Armah, Sheldon Bastacky, Rajiv Dhir and Anil V Parwani

    Citation: Diagnostic Pathology 2009 4:35

    Content type: Research

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  23. Mast cells reside within the connective tissue of a variety of tissues and all vascularized organs. Since 1996, few studies have been performed on mast cell density in gastrointestinal biopsies, mainly in adul...

    Authors: Fatemeh E Mahjoub, Fatemeh Farahmand, Zahra Pourpak, Hoda Asefi and Zahra Amini

    Citation: Diagnostic Pathology 2009 4:34

    Content type: Research

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  24. We are reporting the first Collagenofibrotic Glomerulopathy (CG) in South America. So, this collagen type III glomerulopathy is not limited to Japan but may be found throughout the world.

    Authors: Renata DR Ferreira, Fabiano B Custódio, Camila SO Guimarães, Rosana RM Corrêa and Marlene A Reis

    Citation: Diagnostic Pathology 2009 4:33

    Content type: Case Report

    Published on:

  26. The HVP vaccine is a useful tool for preventing cervical cancer. The purpose of this study is to determine the most frequent HPV genotypes in Equatorial Guinea in order to develop future vaccination strategies...

    Authors: Benjamín García-Espinosa, MaPaz Nieto-Bona, Sonsoles Rueda, Luís Fernando Silva-Sánchez, MaConcepción Piernas-Morales, Patricia Carro-Campos, Luís Cortés-Lambea and Ernesto Moro-Rodríguez

    Citation: Diagnostic Pathology 2009 4:31

    Content type: Research

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  27. Cylindroma of the breast is a very rare lesion which is morphological and immunophenotypically identical to benign dermal cylindroma. We report a breast cylindroma in a previously healthy 62 year old female de...

    Authors: Amr Mahmoud, David H Hill, Martin J O'Sullivan and Michael W Bennett

    Citation: Diagnostic Pathology 2009 4:30

    Content type: Case Report

    Published on:

  28. The caruncle is a modified cutaneous tissue located at the inner canthus that contains hair follicles, accessory lacrimal glands, sweat glands and sebaceous glands. These different types of tissues can give ri...

    Authors: Helena P Solari, M Palis Ventura, Maria Eugenia Orellana, Gustavo A Novais, Devinder P Cheema and Miguel N Burnier Jr

    Citation: Diagnostic Pathology 2009 4:29

    Content type: Research

    Published on:

  30. As there is no optimal treatment of non small cell lung cancer due to its resistance to common chemotherapeutics, we investigated the effect of human placenta-conditioned medium on tumor tissue. The human plac...

    Authors: Sebastian Marwitz, Tobias Zeiser, Holger Schultz, Daniel Kähler, Mahdi Abdullah, Hans-Peter Hauber, Peter Zabel, Ekkehard Vollmer and Torsten Goldmann

    Citation: Diagnostic Pathology 2009 4:27

    Content type: Hypothesis

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  31. Low and high-grade ductal carcinoma in-situ (DCIS) are known to be highly disparate by a multitude of parameters, including progression potential, immunophenotype, gene expression profile and DNA ploidy. In th...

    Authors: Oluwole Fadare, Nathan F Clement and Mohiedean Ghofrani

    Citation: Diagnostic Pathology 2009 4:26

    Content type: Research

    Published on:

  32. Ovarian leiomyoma is a rare benign tumor that accounts for 0.5 to 1% of all benign ovarian tumors. It probably arises from smooth muscle cells in the ovarian hilar blood vessels but there are other possible or...

    Authors: Davor Tomas, Tanja Leniček, Neven Tučkar, Zvonimir Puljiz, Mario Ledinsky and Božo Krušlin

    Citation: Diagnostic Pathology 2009 4:25

    Content type: Case Report

    Published on:

  33. Melanosis refers to abnormal or excessive deposition of melanin pigment in the cells and/or tissue, which can be seen in any organ but commonly in skin and oral mucosa. Melanosis of the urinary bladder is an e...

    Authors: Bo Jin, Syed Y Zaidi, Melvin Hollowell, Christopher Hollowell and Husain Saleh

    Citation: Diagnostic Pathology 2009 4:24

    Content type: Case Report

    Published on:

  34. Anti-neutrophil cytoplasmic antibodies (ANCA) is autoantibodies characteristic of vasculitis diseases. A connection between ANCA and Wegener's granulomatosis was well established. The interaction of both ANCA ...

    Authors: Akiko Uehara, Tadasu Sato, Atsushi Iwashiro and Sou Yokota

    Citation: Diagnostic Pathology 2009 4:23

    Content type: Research

    Published on:

  35. To evaluate the usefulness of this biomarker in the diagnosis of cases of cervical neoplasia we studied the immunohistochemical expression of p16INK4a in a large series of archival cervical biopsies arranged into...

    Authors: Iana Lesnikova, Marianne Lidang, Stephen Hamilton-Dutoit and Jørn Koch

    Citation: Diagnostic Pathology 2009 4:22

    Content type: Research

    Published on:

  37. Because of the poor sensitivity of urinary cytological findings for the diagnosis of especially low grade urinary bladder carcinoma, new molecular diagnostic methods have been proposed. We decided to verify th...

    Authors: Isin Soyuer, Mustafa Sofikerim, Fatma Tokat, Serdar Soyuer and Figen Ozturk

    Citation: Diagnostic Pathology 2009 4:20

    Content type: Research

    Published on:

  39. Adenoid cystic carcinomas are rare tumors with an indolent clinical course, but frequent local relapses. The identification of tumors with a higher relapse risk seems to be interesting. Hence we investigated p...

    Authors: Hans-Ullrich Völker, Matthias Scheich, Annette Berndt, Imme Haubitz, Alexandra Metzger, Hans-Konrad Müller-Hermelink, Ulrike Kämmerer and Melanie Schmidt

    Citation: Diagnostic Pathology 2009 4:18

    Content type: Research

    Published on:

  40. Malignant transformation of mature cystic teratoma is a rare complication. While any of the constituent tissues of a teratoma has the potential to undergo malignant transformation, squamous cell carcinoma is t...

    Authors: Henry B Armah, Anil V Parwani and Aleksandr M Perepletchikov

    Citation: Diagnostic Pathology 2009 4:17

    Content type: Case Report

    Published on:

  42. The recently recognized renal cell carcinomas (RCCs) associated with Xp11.2 translocations (TFE3 transcription factor gene fusions) are rare tumors predominantly reported in children. They comprise at least on...

    Authors: Henry B Armah, Anil V Parwani, Urvashi Surti and Sheldon I Bastacky

    Citation: Diagnostic Pathology 2009 4:15

    Content type: Case Report

    Published on:

  45. Pattern recognition receptors are a key component of the first line host defense against infection, recognizing specific microbial products. We hypothesize that monocyte hyporesponsiveness in human sepsis is a...

    Authors: Bernhard Schaaf, Karen Luitjens, Torsten Goldmann, Tobias van Bremen, Friedhelm Sayk, Christoph Dodt, Klaus Dalhoff and Daniel Droemann

    Citation: Diagnostic Pathology 2009 4:12

    Content type: Research

    Published on:

  46. Primary non-Hodgkin lymphoma (NHL) of the breast represents 0.04–0.5% of malignant lesions of the breast and accounts for 1.7–2.2% of extra-nodal NHL. Most primary cases are of B-cell phenotype and only rare c...

    Authors: Mona RY Bishara, Cathy Ross and Monalisa Sur

    Citation: Diagnostic Pathology 2009 4:11

    Content type: Case Report

    Published on:

  47. Management of endometrial precancerous lesions has been of much debate due to inconsistencies in their classification, natural history and histologic diagnosis. Endometrial hyperplasia constitutes a wide range...

    Authors: Narges Izadi-Mood, Maryam Yarmohammadi, Seyed Ali Ahmadi, Guity Irvanloo, Hayedeh Haeri, Ali Pasha Meysamie and Mahmood Khaniki

    Citation: Diagnostic Pathology 2009 4:10

    Content type: Research

    Published on:

  48. The reliability of gene expression profiling-based technologies to detect transcriptional differences representative of the original samples is affected by the quality of the extracted RNA. It strictly depends...

    Authors: Jai Prakash Muyal, Vandana Muyal, Brajesh Pratap Kaistha, Carola Seifart and Heinz Fehrenbach

    Citation: Diagnostic Pathology 2009 4:9

    Content type: Methodology

    Published on:

  49. Surfactant Protein-A (SP-A) is the most prominent among four proteins in the pulmonary surfactant-system. SP-A is expressed by alveolar epithelial cells type II as well as by a portion of non small cell lung c...

    Authors: Torsten Goldmann, Daniel Kähler, Holger Schultz, Mahdi Abdullah, Dagmar S Lang, Florian Stellmacher and Ekkehard Vollmer

    Citation: Diagnostic Pathology 2009 4:8

    Content type: Review

    Published on:

  50. Clear cell renal cell carcinomas (ccRCCs) constitute the most common renal carcinomas, characterized by a relatively aggressive clinical course. Thus, scientific research is targeting towards the identificatio...

    Authors: Vassilis Samaras, Maria Tsopanomichalou, Angeliki Stamatelli, Christos Arnaoutoglou, Efstathios Samaras, Marianthi Arnaoutoglou, Hercules Poulias and Calypso Barbatis

    Citation: Diagnostic Pathology 2009 4:7

    Content type: Research

    Published on:

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